Trioday Tablets | Lamivudine + Tenofovir Disoproxil Fumarate + Efavirenz

Trioday Tablets is a fixed-dose combination antiretroviral medicine used for the treatment of Human Immunodeficiency Virus (HIV-1) infection. It contains three well-established antiviral agents: Lamivudine 300 mg, Tenofovir Disoproxil Fumarate 300 mg, and Efavirenz 600 mg.

This powerful once-daily combination helps suppress HIV replication, reduce viral load, and improve immune function. Due to its effectiveness, affordability, and convenience, Trioday Tablets are widely used in global HIV treatment programs, especially in resource-limited settings.

Active Ingredients & Composition

Each film-coated tablet contains:

• Lamivudine – 300 mg

• Tenofovir Disoproxil Fumarate – 300 mg

• Efavirenz – 600 mg

How Trioday Tablets Work

Trioday Tablets combine three antiretroviral agents that act at different stages of the HIV life cycle:

Lamivudine

A nucleoside reverse transcriptase inhibitor (NRTI) that blocks HIV from making copies of itself.

Tenofovir Disoproxil Fumarate

An NRTI that prevents viral DNA synthesis, helping reduce viral load and slow disease progression.

Efavirenz

A non-nucleoside reverse transcriptase inhibitor (NNRTI) that directly inhibits the reverse transcriptase enzyme.

Together, these medicines provide potent viral suppression when taken consistently.

Uses of Trioday Tablets

Trioday Tablets are used for:

• Treatment of HIV-1 infection

• First-line antiretroviral therapy (ART)

• Reducing HIV viral load

• Improving CD4 cell count

• Preventing HIV-related complications

• Long-term HIV disease management

⚠️ Trioday Tablets do not cure HIV but help control the infection effectively.

Benefits of Trioday Tablets

• Once-daily dosing

• WHO-recommended components

• Strong and sustained viral suppression

• Cost-effective HIV treatment

• Improves patient compliance

• Widely used in international HIV programs

How to Take Trioday Tablets

• Take one tablet once daily

• Preferably take at bedtime

• Take on an empty stomach to reduce side effects

• Swallow whole with water

Dosage & Administration

Recommended Dosage

• Adults: One tablet once daily, as prescribed

Missed Dose

• Take as soon as remembered

• Skip if near next dose

• Do not double the dose

Overdose

Seek immediate medical attention in case of overdose.

Directions for Use

• Use strictly under medical supervision

• Do not stop treatment without consulting your doctor

• Regular monitoring of liver and kidney function is advised

• Maintain strict daily adherence to avoid resistance

Safety Information & Warnings

Prescription Only Medicine (Rx)

Before taking Trioday Tablets, inform your doctor if you have:

• Liver disease (including hepatitis B or C)

• Kidney problems

• Mental health conditions

• Pregnancy or breastfeeding plans

⚠️ Efavirenz may cause dizziness, vivid dreams, or mood changes, especially during the initial weeks.

Possible Side Effects

Common Side Effects

• Dizziness

• Headache

• Nausea

• Fatigue

• Abnormal dreams

Serious Side Effects (Rare)

• Severe liver problems

• Skin rash

• Psychiatric symptoms

• Lactic acidosis

Seek immediate medical attention if severe symptoms occur.

Drug Interactions

Trioday Tablets may interact with:

• Rifampicin

• Certain antifungals

• Anti-epileptic medicines

• Herbal supplements like St. John’s Wort

Always inform your healthcare provider about all medicines you are taking.

Storage Instructions

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children

• Do not use after expiry date

Different Brand Names Available in the Market

The same combination is available under different brand names, including:

• Trioday Tablets

• Atripla® (brand equivalent)

• Other approved generic combinations

Availability may vary by country.

Frequently Asked Questions (FAQs)

Is Trioday Tablets a cure for HIV?

No, it controls HIV but does not cure it.

Can Trioday Tablets be taken long-term?

Yes, under medical supervision.

Why is Trioday taken at night?

Efavirenz may cause dizziness, so bedtime dosing reduces discomfort.

Why Choose Trioday Tablets?

• Proven antiretroviral combination

• Recommended in global HIV programs

• High efficacy and affordability

• Simple once-daily regimen

• Suitable for long-term HIV management

Important Note

Unnati Pharmax is Authroized dealer of Pharmaceutical medicine in all over the globe.

Philippines Health Technology Assessment Council (HTAC)

Philippines Department of Health (DOH) – HIV Program

CDC – HIV Treatment Basics