Tenvir AF 25 mg Tablets | Tenofovir Alafenamide

Tenvir AF 25 mg Tablets is a prescription antiviral medicine used for the treatment of Human Immunodeficiency Virus (HIV-1) infection and Chronic Hepatitis B (HBV) infection. It contains Tenofovir Alafenamide 25 mg, an advanced nucleotide reverse transcriptase inhibitor (NRTI) designed to deliver effective antiviral activity with improved kidney and bone safety.

Tenvir AF 25 mg Tablets are widely prescribed as part of combination antiretroviral therapy (ART) and are suitable for long-term treatment in HIV and Hepatitis B patients.

Active Ingredient & Composition

Each film-coated tablet contains:

• Tenofovir Alafenamide – 25 mg

How Tenvir AF 25 mg Tablets Work

Tenofovir Alafenamide works by:

• Converting into its active form (tenofovir diphosphate) inside infected cells

• Inhibiting the reverse transcriptase enzyme

• Preventing viral DNA replication

• Reducing HIV and HBV viral load

Compared to Tenofovir Disoproxil Fumarate (TDF), Tenofovir Alafenamide provides higher intracellular drug levels with lower plasma exposure, reducing the risk of side effects.

Uses of Tenvir AF 25 mg Tablets

Tenvir AF 25 mg Tablets are indicated for:

• Treatment of HIV-1 infection (in combination with other antiretroviral agents)

• Treatment of Chronic Hepatitis B infection

• Long-term antiviral therapy

• Reducing HIV viral load

• Preventing liver damage due to Hepatitis B

⚠️ This medicine does not cure HIV or Hepatitis B but helps control the infection effectively.

Benefits of Tenvir AF 25 mg Tablets

• Improved kidney and bone safety

• Suitable for long-term use

• Lower systemic exposure to tenofovir

• WHO-recommended active ingredient

• Once-daily dosing

• High antiviral effectiveness

How to Take Tenvir AF 25 mg Tablets

• Take one tablet once daily

• Can be taken with or without food

• Swallow whole with water

• Take at the same time each day

Dosage & Administration

Recommended Dosage

• Adults: 25 mg once daily, or as directed by the physician

Missed Dose

• Take as soon as remembered

• Skip if close to next dose

• Do not double the dose

Overdose

In case of overdose, seek immediate medical help.

Directions for Use

• Use strictly under medical supervision

• Do not discontinue treatment without consulting your doctor

• Regular monitoring of kidney and liver function is advised

• Maintain strict adherence for best viral suppression

Safety Information & Warnings

Prescription Only Medicine (Rx)

Inform your doctor if you have:

• Liver disease or Hepatitis B

• Kidney impairment

• Bone disorders

• Pregnancy or breastfeeding plans

⚠️ Discontinuation may cause severe worsening of Hepatitis B in co-infected patients.

Possible Side Effects

Common Side Effects

• Headache

• Nausea

• Fatigue

• Diarrhea

Serious Side Effects (Rare)

• Lactic acidosis

• Liver toxicity

• Severe allergic reactions

Seek medical attention if serious symptoms occur.

Drug Interactions

Tenvir AF 25 mg Tablets may interact with:

• Other antiretroviral drugs

• Rifampicin and anticonvulsants

• Certain antivirals

• Herbal products like St. John’s Wort

Always inform your healthcare provider about all medicines you are taking.

Storage Instructions

• Store below 30°C

• Protect from moisture and direct sunlight

• Keep out of reach of children

• Do not use after expiry date

Different Brand Names Available in the Market

Tenofovir Alafenamide 25 mg is available under various brand names, including:

• Tenvir AF 25 mg Tablets

• Vemlidy®

• Other approved generic brands

Availability may vary by country.

Frequently Asked Questions (FAQs)

Is Tenvir AF safer than Tenofovir DF?

Yes, it offers better kidney and bone safety.

Can Tenvir AF 25 mg be used long-term?

Yes, with regular medical monitoring.

Is Tenvir AF used alone for HIV?

No, it is used as part of combination ART.

Why Choose Tenvir AF 25 mg Tablets?

• Advanced tenofovir formulation

• Proven antiviral effectiveness

• Improved long-term safety

• Suitable for HIV and Hepatitis B patients

• Trusted global therapy option

Important Note

Unnati Pharmax is Authroized dealer of Pharmaceutical medicine in all over the globe.

Gilead Sciences Ltd, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 18th May 2023],

Gilead Sciences, US Food, and Drug Administration, [ Revised on Feb 2020] [ Accessed on 18th May 2023],