Introduction
Taffic Tablet is a prescription medicine that combines three active ingredients: Tenofovir alafenamide, Emtricitabine, and Dolutegravir. It belongs to the class of antiretroviral medicines and is used in the treatment of HIV-1 infection. Taffic helps reduce the amount of virus in the blood (viral load), improve immunity, and lower the chances of HIV-related complications. While it does not cure HIV/AIDS, it plays a vital role in controlling the infection and improving the quality of life for patients.
Composition
Each Taffic Tablet contains:
-
Dolutegravir (50 mg) – an integrase inhibitor
-
Emtricitabine (200 mg) – a nucleoside reverse transcriptase inhibitor (NRTI)
-
Tenofovir alafenamide (25 mg) – a nucleotide reverse transcriptase inhibitor (NtRTI)
This fixed-dose combination makes it convenient for patients to take just one tablet daily.
How Taffic Tablets Work
HIV multiplies in the body by entering healthy CD4 cells (immune cells) and using them to replicate.
-
Dolutegravir prevents the integration of viral DNA into human DNA.
-
Emtricitabine and Tenofovir alafenamide block the reverse transcriptase enzyme, preventing the virus from making new copies.
Together, these actions reduce the viral load and help maintain immune function.
Uses of Taffic Tablets
-
Primary Use: Treatment of HIV-1 infection in adults and adolescents (12 years and older, weighing at least 40 kg).
-
Helps improve immune response by increasing CD4 cell count.
-
Reduces HIV-related complications such as opportunistic infections.
-
Part of long-term therapy to achieve viral suppression.
Dosage & Administration
-
Recommended Dose: One tablet taken once daily with or without food.
-
Take the medicine at the same time every day for best results.
-
Do not skip doses, as irregular use may lead to drug resistance.
-
It must be taken under medical supervision only.
Side Effects of Taffic Tablets
Like all medicines, Taffic may cause side effects, though not everyone experiences them. Common side effects include:
-
Headache
-
Nausea
-
Diarrhea
-
Fatigue
-
Trouble sleeping
Serious but rare side effects:
-
Liver problems (yellowing of eyes/skin, dark urine)
-
Kidney dysfunction
-
Mood changes or depression
-
Severe allergic reactions
If you experience severe side effects, seek medical help immediately.
Precautions
-
Inform your doctor if you have a history of liver disease (including hepatitis B or C), kidney problems, or mental health disorders.
-
Pregnant or breastfeeding women should consult their doctor before use.
-
Do not take Taffic with other antiretroviral drugs unless prescribed.
-
Avoid alcohol, as it may increase the risk of liver damage.
-
Keep taking the medication even if you feel well, as stopping can worsen HIV infection.
Storage
-
Store below 30°C in a dry place.
-
Keep away from direct sunlight and moisture.
-
Keep out of reach of children.
FAQs About Taffic Tablets
1. What is Taffic?
HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). TAFFIC contains the medicines bictegravir, emtricitabine, and tenofovir alafenamide. It is not known if TAFFIC is safe and effective in children who weigh less than 25 kg.
TAFFIC does not cure HIV-1 or AIDS. HIV-1 is the virus that causes AIDS.
2. What is the most important information I should know about TAFFIC ?
TAFFIC may cause serious side effects:
Worsening of hepatitis B (HBV) infection. If you have both HIV-1 and HBV and stop taking TAFFIC, your HBV may suddenly get worse. Do not stop taking TAFFIC without first talking to your healthcare provider, as they will need to monitor your health.
3. Who should not take TAFFIC ?
Patient who are taking following
4. What are the possible side effects of TAFFIC ?
Serious side effects of TAFFIC may also include:
Changes in your immune system. Your immune system may get stronger and begin to fight infections. Tell your healthcare provider if you have any new symptoms after you start taking TAFFIC.
Kidney problems, including kidney failure. Your healthcare provider should do blood and urine tests to check your kidneys. If you develop new or worse kidney problems, they may tell you to stop taking TAFFIC.
Too much lactic acid in your blood (lactic acidosis), which is a serious but rare medical emergency that can lead to death. Tell your healthcare provider right away if you get these symptoms: weakness or being more tired than usual, unusual muscle pain, being short of breath or fast breathing, stomach pain with nausea and vomiting, cold or blue hands and feet, feel dizzy or lightheaded, or a fast or abnormal heartbeat.
Severe liver problems, which in rare cases can lead to death. Tell your healthcare provider right away if you get these symptoms: skin or the white part of your eyes turns yellow, dark “tea-colored” urine, light-colored stools, loss of appetite for several days or longer, nausea, or stomach-area pain.
The most common side effects of TAFFIC in clinical studies were diarrhea, nausea, and headache. Tell your healthcare provider if you have any side effects that bother you or don’t go away.
5. What should I tell my healthcare provider before taking TAFFIC ?
All your health problems. Be sure to tell your healthcare provider if you have or have had any kidney or liver problems, including hepatitis virus infection.
All the medicines you take, including prescription and over-the-counter medicines, antacids, laxatives, vitamins, and herbal supplements. TAFFIC and other medicines may affect each other. Keep a list of all your medicines and show it to your healthcare provider and pharmacist, and ask if it is safe to take TAFFIC with all of your other medicines.
If you are pregnant or plan to become pregnant. It is not known if TAFFIC can harm your unborn baby. Tell your healthcare provider if you become pregnant while taking TAFFIC.
If you are breastfeeding (nursing) or plan to breastfeed. Do not breastfeed. HIV-1 can be passed to the baby in breast milk.
6. How should I store TAFFIC ?
Keep TAFFIC and all medicines out of reach of children.
Reviews
There are no reviews yet.