Trustiva Tablets | Emtricitabine + Tenofovir Disoproxil Fumarate + Efavirenz

Trustiva Tablets is a fixed-dose combination antiretroviral medicine used for the treatment of Human Immunodeficiency Virus (HIV-1) infection. It contains three proven antiviral agents: Emtricitabine 200 mg, Tenofovir Disoproxil Fumarate 300 mg, and Efavirenz 600 mg.

This once-daily combination works by suppressing HIV replication, reducing viral load, and strengthening the immune system. Due to its effectiveness and affordability, Trustiva Tablets are widely used in global HIV treatment programs and recommended as a first-line antiretroviral therapy (ART) in many settings.

Active Ingredients & Composition

Each film-coated tablet contains:

• Emtricitabine – 200 mg

• Tenofovir Disoproxil Fumarate – 300 mg

• Efavirenz – 600 mg

How Trustiva Tablets Work

Trustiva Tablets combine two NRTIs and one NNRTI, attacking HIV at different stages of its life cycle:

Emtricitabine

Blocks the reverse transcriptase enzyme, preventing HIV from replicating.

Tenofovir Disoproxil Fumarate

Inhibits viral DNA synthesis, reducing viral load and slowing disease progression.

Efavirenz

Directly inhibits reverse transcriptase, preventing conversion of viral RNA into DNA.

Together, these medicines provide strong and sustained viral suppression.

Uses of Trustiva Tablets

Trustiva Tablets are used for:

• Treatment of HIV-1 infection

• First-line antiretroviral therapy (ART)

• Reducing HIV viral load

• Improving CD4 cell count

• Preventing HIV-related complications

• Long-term HIV disease management

⚠️ Trustiva Tablets do not cure HIV but help control the infection effectively.

Benefits of Trustiva Tablets

• Once-daily dosing

• WHO-recommended antiretroviral components

• High effectiveness in viral suppression

• Cost-effective HIV treatment

• Improves patient compliance

• Widely accepted in global HIV programs

How to Take Trustiva Tablets

• Take one tablet once daily

• Preferably take at bedtime

• Take on an empty stomach to reduce side effects

• Swallow whole with water

Dosage & Administration

Recommended Dosage

• Adults: One tablet once daily, as prescribed

Missed Dose

• Take as soon as remembered

• Skip if close to the next dose

• Do not double the dose

Overdose

Seek immediate medical attention in case of overdose.

Directions for Use

• Use strictly under medical supervision

• Do not stop treatment without consulting your doctor

• Regular monitoring of liver and kidney function is advised

• Maintain strict daily adherence to prevent resistance

Safety Information & Warnings

Prescription Only Medicine (Rx)

Inform your doctor before use if you have:

• Liver disease (including hepatitis B or C)

• Kidney problems

• Mental health conditions

• Pregnancy or breastfeeding plans

⚠️ Efavirenz may cause dizziness, abnormal dreams, or mood changes, especially during initial treatment.

Possible Side Effects

Common Side Effects

• Dizziness

• Headache

• Nausea

• Fatigue

• Abnormal dreams

Serious Side Effects (Rare)

• Severe liver problems

• Skin rash

• Psychiatric symptoms

• Lactic acidosis

Seek medical help if severe side effects occur.

Drug Interactions

Trustiva Tablets may interact with:

• Rifampicin

• Certain antifungal medicines

• Anti-epileptic drugs

• Herbal products such as St. John’s Wort

Always inform your doctor about all medicines you are taking.

Storage Instructions

• Store below 30°C

• Protect from moisture and sunlight

• Keep out of reach of children

• Do not use after expiry date

Different Brand Names Available in the Market

The same combination is available under different brand names, including:

• Trustiva Tablets

• Atripla®

• Other approved generic combinations

Availability may vary by country.

Frequently Asked Questions (FAQs)

Is Trustiva Tablets a cure for HIV?

No, it controls HIV but does not cure it.

Why is Trustiva taken at night?

Efavirenz may cause dizziness, so bedtime dosing reduces discomfort.

Can Trustiva Tablets be used long-term?

Yes, under regular medical supervision.

Why Choose Trustiva Tablets?

• Proven triple-drug antiretroviral combination

• Recommended in international HIV guidelines

• Simple once-daily regimen

• Suitable for long-term HIV management

• Trusted and widely used formulation

Important Note

Unnati Pharmax is Authroized dealer of Pharmaceutical medicine in all over the globe.

U.S. FDA – Atripla (Efavirenz Combination) Drug Label

NIH – HIV Clinical Guidelines

HIV Clinic 

Philippines Department of Health (DOH) – HIV Program

Philippines Health Technology Assessment Council (HTAC)