Description:
XTIDE 160mg Tablet contains Enzalutamide, an androgen receptor inhibitor used in the treatment of prostate cancer. It is mainly prescribed for men with metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
Enzalutamide works by blocking the action of male hormones (androgens such as testosterone) that stimulate the growth of prostate cancer cells. Unlike some other hormonal therapies, it directly blocks androgen receptors, preventing the cancer cells from using testosterone to grow and divide.
Key Benefits:
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Effective in advanced and resistant forms of prostate cancer.
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Slows disease progression and reduces symptoms.
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Improves overall survival rates and quality of life.
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Taken orally, offering a non-invasive treatment option.
Common Side Effects:
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Fatigue and weakness
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Hot flashes
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Headache and dizziness
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High blood pressure
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Joint or back pain
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Loss of appetite
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Increased risk of falls and seizures (rare)
Precautions:
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Not recommended for women or children.
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Should not be used during pregnancy or breastfeeding.
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Inform your doctor about any history of seizures, heart problems, or liver issues.
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Regular monitoring of blood pressure, liver function, and PSA levels is required.
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May interact with other medicines (especially blood thinners and seizure medications).
Dosage & Administration:
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Typically prescribed as 160mg once daily (equivalent to four 40mg capsules), with or without food.
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The dosage should be taken at the same time each day.
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Do not stop treatment without consulting your doctor.
FAQs:
Q1: What is XTIDE 160mg Tablet used for?
It is used in the treatment of metastatic castration-resistant and castration-sensitive prostate cancer.
Q2: How does XTIDE (Enzalutamide) work?
It blocks the action of androgens by binding to androgen receptors, preventing prostate cancer cells from growing.
Q3: Can XTIDE cure prostate cancer?
No, it does not cure prostate cancer but it slows progression, reduces symptoms, and extends survival.
Q4: What precautions should I follow while on XTIDE?
Avoid driving or operating heavy machinery if you feel dizzy or weak, and inform your doctor if you have a history of seizures or heart problems.
Q5: How long will I need to take XTIDE?
Treatment is usually long-term and continues as long as it is effective and tolerated by the patient, under doctor’s supervision.
Reference:-
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Full FDA label for XTANDI (enzalutamide) capsules/tablets: https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/213674s010%2C203415s022lbl.pdf FDA Access Data
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EMA product information (SmPC) for XTANDI: https://www.ema.europa.eu/en/documents/product-information/xtandi-epar-product-information_en.pdf European Medicines Agency (EMA)
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Astellas Canada product monograph for XTANDI (latest): https://www.astellas.com/ca/system/files/pdf/xtandi_pm_05jan2024_en.pdf
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