Obnyx Enzalutamide 40 MG (Xtandi)

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Brand Name

Enzanamo Capsule

Generic Name

Enzalutamide

Strength

40 mg

Drug Class

Androgen Receptor (AR) Inhibitor / Anti-androgen

Therapeutic Class

Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)

Mechanism of Action

Enzanamo is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It blocks the effects of male hormones (androgens/testosterone) by inhibiting AR binding, preventing AR nuclear translocation, and impairing AR interaction with DNA, thus stopping prostate cancer cell growth.

Indications (Uses)

Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).

Dosage & Administration

Recommended Dose: The standard dose is 160 mg once daily (four 40 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.

SKU: 0375 Category: Brand:

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Product introduction

Obnyx Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Obnyx Capsule is used in the treatment of cancer of the prostate gland. It may also treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Obnyx Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it strictly as your doctor has advised. Taking it incorrectly or taking too much can cause severe side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness, and high blood pressure are common side effects of this medicine. Other than this, yellowing of the skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells and liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight; hence take extra caution while going out.

Before taking it, tell your doctor if you have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect or be affected by this, so let your doctor know all your medications. You may be asked to monitor blood glucose levels while on treatment regularly. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is essential to avoid pregnancy.

There is a Patient Support Program / Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.


Uses of Obnyx Capsule

  • Polycystic ovarian syndrome (PCOS)
  • Prostate cancer
  • Excessive hair growth

Benefits of Obnyx Capsule

In Polycystic ovarian syndrome (PCOS)

PCOS is a hormonal disorder that can cause irregular periods, ovarian cysts, and symptoms like acne or excessive hair growth. Obnyx Capsule helps block the effects of certain hormones that contribute to these symptoms, supporting hormonal balance and improving menstrual regularity and skin health.

Side effects of Obnyx Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Obnyx

  • Headache
  • Hot flashes
  • Weakness
  • High blood pressure
  • Fatigue
  • Decreased appetite
  • Constipation
  • Dry skin
  • Itching
  • Fall
  • Fracture

How to use Obnyx Capsule

Take this medicine in the dose and duration as advised by your doctor. Obnyx Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Obnyx Capsule works

Obnyx Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Safety advice

warnings

Alcohol

UNSAFE
It is unsafe to consume alcohol with Obnyx Capsule.
warnings

Pregnancy

CONSULT YOUR DOCTOR
Obnyx Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
warnings

Breast feeding

UNSAFE
Obnyx Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
warnings

Driving

UNSAFE
Obnyx Capsule may cause side effects which could affect your ability to drive.
warnings

Kidney

CAUTION
Obnyx Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Obnyx Capsule may be needed. Please consult your doctor.
warnings

Liver

CAUTION
Obnyx Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Obnyx Capsule may be needed. Please consult your doctor.

What if you forget to take Obnyx Capsule?

If you miss a dose of Obnyx Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

  • You have been prescribed Obnyx Capsule for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • Do not drive or do anything requiring concentration unless you know how Obnyx Capsule affects you.
  • It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Obnyx Capsule.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication without talking to your doctor first.

FAQs

What is Obnyx Capsule used for?

Obnyx Capsule is used to treat prostate cancer that has spread, or is resistant to hormone therapy. It works by blocking the effect of male hormones (androgens) that help cancer cells grow.

Who should not take Obnyx Capsule?

People should not take Obnyx Capsule if they are allergic to it or any of its ingredients. It is also not recommended for women, especially during pregnancy, due to the risk of harm to an unborn baby.

Can Obnyx Capsule cause seizures?

Yes, Obnyx Capsule can increase the risk of seizures. Patients with a history of seizures, brain injury, stroke, or those taking medicines that lower the seizure threshold need extra caution.

What are the serious side effects of Obnyx Capsule?

Serious side effects of Obnyx Capsule may include seizures, severe allergic reactions, sudden chest pain, shortness of breath, swelling in legs, falls, memory problems, or unusual bleeding. Seek medical attention right away if these occur.

Can Obnyx Capsule affect memory or thinking?

Yes, Obnyx Capsule may cause problems such as memory loss, confusion, trouble concentrating, or a higher risk of falls. These side effects may impact daily activities.

Does Obnyx Capsule affect blood pressure or heart health?

Yes, Obnyx Capsule can cause high blood pressure, and may increase the risk of heart problems such as heart attack, or heart failure. Regular monitoring is important, especially if you already have heart disease.

Does Obnyx Capsule affect fertility in men?

Yes, Obnyx Capsule may reduce fertility in men, and can harm an unborn child if the father is taking it during conception. Effective contraception is recommended during treatment, and for at least 3 months after stopping.

References:-

Brand Name

Enzanamo Capsule

Generic Name

Enzalutamide

Strength

40 mg

Drug Class

Androgen Receptor (AR) Inhibitor / Anti-androgen

Therapeutic Class

Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)

Mechanism of Action

Enzanamo is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It blocks the effects of male hormones (androgens/testosterone) by inhibiting AR binding, preventing AR nuclear translocation, and impairing AR interaction with DNA, thus stopping prostate cancer cell growth.

Indications (Uses)

Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).

Dosage & Administration

Recommended Dose: The standard dose is 160 mg once daily (four 40 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.

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Obnyx 40mg Enzalutamide Capsules for prostate cancer treatment. Obnyx Enzalutamide 40 MG (Xtan...

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