Nindanib 150 SoftGelatin Capsule|Nintedanib for IPF & Cancer

Product introduction

Nindanib 150 Soft Gelatin Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.

Nindanib 150 Soft Gelatin Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.

Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Nindanib Soft Gelatin Capsule

Treatment of Idiopathic pulmonary fibrosis
Treatment of Non-small cell lung cancer

Benefits of Nindanib Soft Gelatin Capsule

In Treatment of Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Nindanib 150 Soft Gelatin Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

Side effects of Nindanib Soft Gelatin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nindanib

Abdominal pain
Diarrhea
Nausea
Vomiting
Abnormal liver function tests
Loss of appetite
Headache
Weight loss
High blood pressure

How to use Nindanib Soft Gelatin Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nindanib 150 Soft Gelatin Capsule is to be taken with food.

How Nindanib Soft Gelatin Capsule works

Nindanib 150 Soft Gelatin Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nindanib 150 Soft Gelatin Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Nindanib 150 Soft Gelatin Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Nindanib 150 Soft Gelatin Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Nindanib 150 Soft Gelatin Capsule may cause side effects which could affect your ability to drive.
You may feel sick after taking this medicine and this could affect your driving.

Kidney

CAUTION

Nindanib 150 Soft Gelatin Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Nindanib 150 Soft Gelatin Capsule may be needed. Please consult your doctor.
There is limited information available on the use of Nindanib 150 Soft Gelatin Capsule in these patients.

Liver

CAUTION

Nindanib 150 Soft Gelatin Capsule should be used with caution in patients with liver disease. Dose adjustment of Nindanib 150 Soft Gelatin Capsule may be needed. Please consult your doctor.
Use of Nindanib 150 Soft Gelatin Capsule is not recommended in patients with moderate to severe liver disease.

What if you forget to take Nindanib Soft Gelatin Capsule?

If you miss a dose of Nindanib 150 Soft Gelatin Capsule, skip it and continue with your normal schedule. Do not double the dose.

FAQs

What is Nindanib 150 Soft Gelatin Capsule used for?

Nindanib 150 Soft Gelatin Capsule is a medication that helps slow down scarring or stiffness in the lungs. It is mainly used to treat conditions like pulmonary fibrosis (lung scarring) and certain types of lung diseases. It works by blocking substances in your body that cause lung tissues to become thick and stiff. Nindanib 150 Soft Gelatin Capsule helps slow down lung function decline, but it is not a cure.

Can Nindanib 150 Soft Gelatin Capsule cause serious health problems?

Yes, though rare, Nindanib 150 Soft Gelatin Capsule may cause liver injury, heart attack, bleeding problems, kidney issues (protein in urine) and gastrointestinal perforation. Your doctor will monitor you regularly to reduce these risks.

Is Nindanib 150 Soft Gelatin Capsule safe for people with liver or kidney problems?

Nindanib 150 Soft Gelatin Capsule is not recommended for moderate or severe liver disease. In mild cases, the dose is usually reduced. Nindanib 150 Soft Gelatin Capsule should also be used with caution in kidney impairment, and monitoring is essential.

Who should avoid taking Nindanib 150 Soft Gelatin Capsule?

Nindanib 150 Soft Gelatin Capsule should be avoided in individuals if they are pregnant or planning pregnancy, have severe liver problems, have had recent stomach surgery or are at high risk of bleeding or blood clots. There are no official contraindications, but caution is advised in these specific groups.

What should I do if I get diarrhea while on Nindanib 150 Soft Gelatin Capsule?

Diarrhea is common during Nindanib 150 Soft Gelatin Capsule treatment. Your doctor may advise using anti-diarrheal medicine early. Drink fluids and contact your doctor if it is severe or long-lasting, as they may adjust your dose.

Can Nindanib 150 Soft Gelatin Capsule reverse lung damage?

No, Nindanib 150 Soft Gelatin Capsule does not reverse fibrosis (lung scarring), but it slows its progression, helping to preserve lung function and potentially improve quality of life over time.

What foods should I avoid while taking Nindanib 150 Soft Gelatin Capsule?

While there are not specific foods you should avoid, eating a light meal when taking Nindanib 150 Soft Gelatin Capsule can help reduce stomach upset. If you experience diarrhea, avoid spicy, fatty, or junk foods that might make it worse.

How long does it take for Nindanib 150 Soft Gelatin Capsule to work?

Nindanib 150 Soft Gelatin Capsule works gradually to slow down lung scarring. It is not a quick-relief medication, and it may take several weeks or months before you notice improvements. Your doctor will monitor your progress through regular check-ups and tests.

When should I contact my doctor while taking Nindanib 150 Soft Gelatin Capsule?

Contact your doctor immediately if you experience severe diarrhea that does not improve, unusual bleeding or bruising, severe stomach pain, yellowing of skin or eyes, dark urine and fever with infection symptoms.

TRUSTED Anti Cancer MEDICINE PROVIDER – UNNATI PHARMAX

Reference:-

European Regulatory Source

EMA – Neulasta (Pegfilgrastim) EPAR: The European Public Assessment Report for the original pegfilgrastim product (Neulasta), including dosing, indications (e.g., prevention of chemotherapy-induced neutropenia), mechanism, and safety profile.
https://www.ema.europa.eu/en/medicines/human/EPAR/neulasta European Medicines Agency (EMA)

Medical & Reference Resources

DrugBank – Pegfilgrastim Overview: Detailed pharmacology, mechanism of action, and a list of biosimilar brand names such as Neulasta, Pelmeg, Udenyca, Ziextenzo, etc.
https://go.drugbank.com/drugs/DB00019 DrugBankWikipedia
Wikipedia – Pegfilgrastim: A comprehensive overview of pegfilgrastim, including its regulatory history (approval in US & EU since 2002) and biosimilar landscape.
https://en.wikipedia.org/wiki/Pegfilgrastim

Brand Name	Nindanib 150
Generic Name	Nintedanib
Strength	150 mg
Dosage Form	Soft Gelatin Capsule
Therapeutic Class	Tyrosine Kinase Inhibitor / Anti-fibrotic agent
Packaging	Strip / Bottle (commonly 10 or 30 capsules)
Storage	Store below 30°C, protect from moisture and direct sunlight

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Product introduction

Uses of Nindanib Soft Gelatin Capsule

Benefits of Nindanib Soft Gelatin Capsule

In Treatment of Idiopathic pulmonary fibrosis