Lynide Lenalidomide 25 MG (Revlimid)

Product Introduction

Lynide 25mg Capsule belongs to a group of medicines that affect how your immune system works. It is used in the treatment of multiple myeloma and myelodysplastic syndrome (MDS).

Lynide 25mg Capsule can be taken with or without food, but try to take it at the same time every day to get the best results. Your doctor will decide the correct dose and duration of your treatment depending on your condition, your response to the medicine, and other medications you may be taking. Follow your doctor’s instructions carefully. Taking more than the prescribed dose or using it incorrectly may cause serious side effects. It may take a few weeks or months to notice improvement, so do not stop taking this medicine unless advised by your doctor.

Common side effects include headache, weakness, nausea, rash, and dizziness. This medicine may also reduce the number of blood cells (both red and white blood cells), increasing your risk of infections or bleeding. Therefore, it’s advised to avoid contact with sick individuals and to be cautious during activities that may cause bruising or injury. Regular blood tests are recommended to monitor your blood cell count and ensure safe treatment.

Before starting Lynide 25mg Capsule, inform your healthcare provider about all medications you are taking. This medicine is not recommended during pregnancy or breastfeeding. Both men and women must use effective contraception during treatment and for at least 4 weeks after stopping the medication. Also, ensure proper hydration by drinking plenty of fluids.

Uses of Lynide Capsule

• Multiple Myeloma

• Treatment of Myelodysplastic Syndrome

Benefits of Lynide Capsule

In Treatment of Myelodysplastic Syndrome (MDS)

Myelodysplastic syndromes are a group of blood disorders where the bone marrow fails to produce enough healthy blood cells, leading to anemia, infections, or bleeding. Lynide 25mg Capsule helps in improving blood cell production by supporting immune system function and bone marrow activity.

It helps reduce dependence on blood transfusions and improves overall energy levels and well-being. Continuous monitoring is essential to ensure safety and effectiveness during treatment.

Side Effects of Lynide Capsule

Most side effects do not require medical attention and disappear as your body adjusts to the medicine. However, consult your doctor if they persist or become troublesome.

Common side effects include:

• Headache

• Nausea

• Rash

• Breathlessness

• Dizziness

• Fatigue

• Low white blood cell count (neutropenia)

• Low platelets (thrombocytopenia)

• Joint or back pain

• Diarrhea

• Itching or rash

• Cough

• Decreased appetite

• Upper respiratory tract infection

• Peripheral edema (swelling)

• Nasopharyngitis (inflammation of nasal and throat passages)

How to Use Lynide Capsule

Take this medicine in the dose and duration as advised by your doctor.
Lynide 25mg Capsule may be taken with or without food, but it is best to take it at a fixed time every day. Swallow the capsule whole with water; do not crush or chew it.

How Lynide Capsule Works

Lynide 25mg Capsule contains Lenalidomide, an anti-cancer and immunomodulatory medication. It works by:

• Boosting immune cells to attack cancer cells,

• Preventing new blood vessels from forming within tumors (anti-angiogenic effect), and

• Reducing the production of growth factors and cytokines that promote cancer cell survival.

This combined action helps slow or stop cancer cell growth and supports healthy cell production in the bone marrow.

Safety Advice

Alcohol

Consult Your Doctor
It is not known whether alcohol interacts with Lynide 25mg Capsule. Please consult your physician before drinking alcohol while on this medication.

Pregnancy

UNSAFE
Lynide 25mg Capsule is highly unsafe during pregnancy. It can cause severe birth defects or death of the unborn baby. Women must avoid pregnancy and use effective contraception during treatment and for at least 4 weeks after stopping.

Breastfeeding

CONSULT YOUR DOCTOR
Limited human data suggests that Lenalidomide may pass into breast milk and harm the baby. Hence, breastfeeding is not recommended.

Driving

UNSAFE
Lynide 25mg Capsule may cause dizziness, sleepiness, tiredness, or blurred vision, which can affect your ability to drive or operate machinery.

Kidney

CAUTION
Lynide 25mg Capsule should be used cautiously in patients with kidney disease. Dose adjustment may be required. Please consult your doctor.

Liver

CAUTION
Lynide 25mg Capsule should be used with caution in patients with liver impairment. Dose adjustments may be necessary as per medical advice.

What if You Forget to Take a Dose?

If you miss a dose, take it as soon as you remember.
If it’s almost time for your next scheduled dose, skip the missed dose — do not double the dose to catch up.

Quick Tips

• Regular blood tests are necessary to monitor white cells, platelets, and hemoglobin levels.

• Avoid contact with sick individuals or people having infections.

• Protect your skin from sunlight by using sunscreen or covering exposed areas.

• Stay well hydrated to reduce side effects.

• Not recommended for children under 18 years.

• Women must undergo pregnancy testing before and after treatment.

• Inform your doctor/dentist that you are taking this medicine before any surgery or procedure.

• You may be at risk of developing acute leukemia, severe skin reactions, or heart issues — discuss all potential risks and benefits with your doctor.

FAQs

Can I take Lynide 25mg Capsule on an empty stomach?

Yes, it can be taken with or without food. Take it at the same time every day, as advised by your doctor. Swallow the capsule whole; do not crush or open it.

Can Lynide 25mg Capsule be used in dialysis patients?

Yes. However, for patients on dialysis, the capsule should be taken after dialysis. Dose adjustment may be required.

What are the side effects of Lynide 25mg Capsule?

Common side effects include diarrhea, constipation, loss of appetite, fatigue, rash, dizziness, and neuropathy (tingling or burning in hands/feet). Consult your doctor if symptoms persist.

Can Lynide 25mg Capsule cause new cancers?

Yes. Patients with multiple myeloma who receive melphalan and stem cell transplant with Lynide 25mg Capsule may have a slightly higher risk of developing new cancers such as acute myeloid leukemia (AML) or Hodgkin lymphoma. Discuss your risk with your doctor.

Do I need regular blood tests while on Lynide 25mg Capsule?

Yes. Blood tests are required before starting treatment, weekly for the first 8 weeks, and then at least monthly thereafter to monitor blood counts and treatment safety.

Do I need birth control while using Lynide 25mg Capsule?

Absolutely.

• Women: Use two reliable forms of contraception 4 weeks before, during, and 4 weeks after treatment.

• Men: Use condoms during treatment and for at least 4 weeks after the final dose, even if vasectomized.

References

• Philippines FDA – Drug Registration (Lynide 25mg Capsule):
  https://verification.fda.gov.ph/ALL_DrugProductslist.php/api/ALL_DrugProductsview.php?showdetail=&registration_number=DR-XY48672
  (Official registration for Lenalidomide 25mg capsule confirming local approval.)

• U.S. FDA – Revlimid (Lenalidomide) Drug Label:
  https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021880s049lbl.pdf
  (Full prescribing information including 25mg dosage and usage guidelines.)

• NIH – PubMed Central:
  https://pmc.ncbi.nlm.nih.gov/articles/PMC3430086/
  (Clinical review of Lenalidomide in relapsed and refractory multiple myeloma.)

• NIH – Practice Guidelines and Survival Data:
  https://pmc.ncbi.nlm.nih.gov/articles/PMC5013840/
  (FDA approval summary for Lenalidomide as frontline therapy.)

• International Myeloma Foundation (IMF):
  https://www.myeloma.org/revlimid-lenalidomide
  (Trusted resource for dosage guidance and side effect management.)