Product introduction
Lenvabuzz Capsule is used to treat certain types of cancers like differentiated thyroid cancer, liver cancer, kidney cancer, and endometrial cancer. It works by blocking specific proteins that promote cancer cell growth and spread, and reducing tumor size in affected individuals.
Lenvabuzz Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will determine the right dose and how often you should take it. This will depend on what you are being treated for. The dosage may change over time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects.
Common side effects of this medicine include high blood pressure, bleeding, and diarrhea. It might also cause severe headaches and loss of appetite. If any of these side effects persist or worsen, consult your doctor. They may be able to suggest ways to manage the side effects.
Before taking Lenvabuzz Capsule, tell your doctor if you have heart disease, liver, or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect or be affected by this medicine, so let your doctor know about all the medicines you are taking. Pregnant and breastfeeding women should consult their doctors before starting this medicine, as it may cause harm to the developing baby.
Uses of Lenvabuzz Capsule
- Differentiated Thyroid cancer
- Treatment of Kidney cancer
- Liver cancer
- Treatment of Endometrial cancer
Benefits of Lenvabuzz Capsule
In Differentiated Thyroid cancer
Thyroid is a butterfly-shaped gland located at the base of your neck. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight. Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first. Lenvabuzz Capsule restricts the oxygen supply of the cancer cells and stops its growth as well as further spread. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Side effects of Lenvabuzz Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lenvabuzz
- High blood pressure
- Diarrhea
- Increased bleeding tendency
How to use Lenvabuzz Capsule
Take this medicine in the dose and duration as advised by your doctor. Lenvabuzz Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Lenvabuzz Capsule works
Lenvabuzz Capsule is a tyrosine kinase inhibitor. It works by blocking the oxygen and nutrient supply to cancer cells, due to which they stop growing. And Lenvabuzz Capsule helps in treating thyroid cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lenvabuzz Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lenvabuzz Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Lenvabuzz Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Lenvabuzz Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Lenvabuzz Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lenvabuzz Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Lenvabuzz Capsule should be used with caution in patients with liver disease. Dose adjustment of Lenvabuzz Capsule may be needed. Please consult your doctor.
What if you forget to take Lenvabuzz Capsule?
If you miss a dose of Lenvabuzz Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick tips
- Take it with or without food, preferably at the same time each day.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure, such as severe headache, confusion, problems with your eyesight, nausea, or vomiting.
- It may cause serious bleeding problems. Inform your doctor if you get headaches or stomach pain or if you notice blood in your urine or stools.
- Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.
FAQs
How will I know if Lenvabuzz Capsule is working?
To evaluate if Lenvabuzz Capsule is effective, your doctor may assess your improvement through scans to monitor your tumor. Your doctor can let you know how well you are doing with Lenvabuzz Capsule treatment and if there is any resolution of your tumor.
What are the most serious side effects of Lenvabuzz Capsule I should watch out for?
During Lenvabuzz Capsule treatment, contact your doctor or go to the hospital immediately if you experience serious side effects. These may include high blood pressure, such as severe headaches or chest pain. You may also have heart problems like shortness of breath, swelling, or a fast heartbeat. Bleeding or blood in vomit or stool can occur. Signs of liver or kidney failure include yellowing of the skin, confusion, or dark urine. Other serious symptoms may include severe diarrhea or vomiting, seizures, vision changes, or confusion. These could be signs of posterior reversible encephalopathy syndrome (PRES), a rare brain condition.
Can I stop taking Lenvabuzz Capsule if my symptoms have improved?
No, never stop taking Lenvabuzz Capsule on your own, as doing this may cause your cancer to worsen or spread to other parts of the body. Stopping abruptly without your doctor’s advice may cause serious harm to your body.
Who should avoid taking Lenvabuzz Capsule?
You should avoid taking Lenvabuzz Capsule if you are allergic to lenvatinib or any of its ingredients. Do not take it if you have uncontrolled high blood pressure, have had recent major surgery (as it may delay wound healing), have a hole in the stomach or intestine, or have recently had a stroke or heart attack. Always inform your doctor about your complete medical history before starting Lenvabuzz Capsule treatment to ensure safer, better, and faster results.
Will I need regular check-ups or tests while taking Lenvabuzz Capsule?
Yes, your doctor will check blood pressure, liver function, kidney function, thyroid function, calcium level, protein in urine, heart function (possibly with ECGs), etc. These tests help catch serious problems early.
How long do I have to continue taking Lenvabuzz Capsule?
You should continue the Lenvabuzz Capsule treatment until cancer has not properly resolved. Stopping or modification in the dose should only be done by a doctor once your cancer has resolved and shows no active symptoms.
Does Lenvabuzz Capsule affect my fertility?
Lenvabuzz Capsule may impair fertility. Talk to your doctor about options like egg preservation before starting treatment.
What other precautions should I take during Lenvabuzz Capsule treatment?
While on Lenvabuzz Capsule treatment, you should not have surgery unless your doctor tells you to stop the medicine as it can slow healing, tell your dentist before any dental work (it can increase the risk of jaw problems), and drink plenty of fluids to avoid dehydration, especially if you have diarrhea.
References:-
- Philippines Food and Drug Administration (FDA) – Drug Registration (Specific Product):
- https://verification.fda.gov.ph/drug_productsview.php?showdetail=®istration_number=DR-XY45688
- (Registration entry for Lenvima 4mg Capsule in the Philippines FDA portal, confirming local approval and generic name.)
- U.S. Food and Drug Administration (FDA) – Approval Summary (for HCC Indication):
- https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-lenvatinib-unresectable-hepatocellular-carcinoma
- (FDA approval summary based on the REFLECT trial for unresectable Hepatocellular Carcinoma (HCC).)
- NIH – PubMed Central (PMC) – Thyroid Cancer Dosing Study:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8852210/
- (Randomized study comparing Lenvatinib 18mg vs 24mg in RAI-refractory Differentiated Thyroid Cancer, a key dosing trial.)
- NIH – PubMed Central (PMC) – Advanced Thyroid Cancer Real-World Data:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9032633/
- (Real-world data study on Lenvatinib safety and efficacy, focusing on side effects like hypertension in advanced thyroid cancer.)
- ResearchGate – Review on Efficacy and Safety Across Cancer Types:
- https://www.researchgate.net/publication/304329384_Safety_and_efficacy_profile_of_lenvatinib_in_cancer_therapy_A_systematic_review_and_meta-analysis
- (Meta-analysis of Lenvatinib’s safety and efficacy profile across various cancer therapies)
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