Lenome Lenalidomide 5 MG (Revlimid)

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Brand Name

Lenalid 5 Capsule

Generic Name

Lenalidomide

Strength

5 mg

Drug Class

Immunomodulatory Agent (IMiD) / Anti-neoplastic

Therapeutic Class

Anti-cancer / Treatment for Hematologic Malignancies

Mechanism of Action

Lenalid (Lenalidomide) is an immunomodulator that works by: 1) Enhancing the immune system's attack on cancer cells (T-cell and NK-cell activation). 2) Inhibiting angiogenesis (new blood vessel growth to tumors). 3) Directly suppressing the growth and promoting the programmed cell death (apoptosis) of malignant blood cells.

Indications (Uses)

Used in adults for the treatment of: Multiple Myeloma (MM) (in combination with Dexamethasone or as maintenance therapy), Myelodysplastic Syndromes (MDS) (specifically for transfusion-dependent anemia due to a specific chromosome deletion, $\text{del}(5\text{q})$), Mantle Cell Lymphoma (MCL), and Follicular Lymphoma (FL).

Dosage & Administration

Recommended Dose: The dose is highly variable, prescribed based on disease and renal function ($\text{CrCl}$). Typical starting doses are 10 mg once daily (for MDS or post-transplant MM maintenance) or 25 mg once daily (for MM/MCL combination therapy). Dosing is usually cyclical (e.g., daily for 21 days of a 28-day cycle). How to Take: Swallow capsule whole. Do not open, crush, or chew. Can be taken with or without food, but at the same time each day.

Common Side Effects

Hematologic Toxicity (Neutropenia, Thrombocytopenia, Anemia), Fatigue/Weakness, Diarrhea or Constipation, Nausea, Rash, Fever, Muscle/Joint pain, Dizziness.

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Product Introduction

Lenome 5 Capsule belongs to a group of medicines that modulate how your immune system works. It is primarily used in the treatment of multiple myeloma and myelodysplastic syndromes (MDS) — two conditions that affect the bone marrow and blood cells.

Lenome 5 Capsule can be taken with or without food, but it should be taken at the same time every day for best results. Your doctor will determine the appropriate dose and duration depending on your condition and response to therapy. Do not stop taking this medicine without consulting your doctor, as stopping it suddenly may make your condition worse. It may take several weeks or months before you feel the full benefits of the treatment.

Common side effects of Lenome 5 Capsule include headache, nausea, rash, weakness, dizziness, and fatigue. This medicine can reduce the number of blood cells (red and white) in your body, increasing the risk of infections or bleeding. It is important to have regular blood tests during treatment to monitor your blood cell count. Avoid close contact with anyone suffering from infections like cold or flu and take precautions to minimize bleeding or bruising.

Lenome 5 Capsule may interact with several other medicines, so inform your doctor about all the medications you are currently taking. It is not recommended during pregnancy or breastfeeding. Both men and women should use effective contraception during and after treatment to prevent pregnancy. Drink plenty of water to stay hydrated while taking this medicine.


Uses of Lenome 5 Capsule

  • Multiple Myeloma

  • Treatment of Myelodysplastic Syndrome (MDS)


Benefits of Lenome 5 Capsule

In Treatment of Myelodysplastic Syndrome

Myelodysplastic Syndromes (MDS) are a group of disorders caused by poorly formed or dysfunctional blood cells in the bone marrow. This leads to anemia, fatigue, infections, and increased bleeding tendency.

Lenome 5 Capsule helps improve the production of healthy blood cells by stimulating the immune system and supporting normal bone marrow function. It reduces the need for frequent blood transfusions and helps improve overall quality of life. Regular checkups and monitoring are necessary to ensure safe and effective treatment.


Side Effects of Lenome 5 Capsule

Most side effects are mild and go away as your body adjusts to the medicine. However, consult your doctor if they persist or worsen.

Common Side Effects:

  • Headache

  • Nausea

  • Rash

  • Fatigue

  • Dizziness

  • Breathlessness

  • Decreased white blood cell count (neutropenia)

  • Low platelet count (thrombocytopenia)

  • Joint or back pain

  • Cough

  • Diarrhea

  • Itching

  • Loss of appetite

  • Nasopharyngitis (sore throat and nasal inflammation)

  • Upper respiratory tract infection

  • Swelling in hands or feet (edema)


How to Use Lenome 5 Capsule

Take this medicine exactly as prescribed by your doctor. Swallow the capsule whole with water. Do not crush, chew, or open it. It can be taken with or without food, preferably at the same time each day.


How Lenome 5 Capsule Works

Lenome 5 Capsule contains lenalidomide, an anti-cancer and immunomodulatory medicine. It works by enhancing the immune system, which helps destroy abnormal cells. It also inhibits the growth of new blood vessels that supply tumors (anti-angiogenic effect) and blocks chemical messengers that promote cancer cell growth. This helps in controlling the spread of the disease.


Safety Advice

Alcohol:
⚠️ Consult your doctor.
It is not known whether it is safe to consume alcohol while taking Lenome 5 Capsule.

Pregnancy:
🚫 Unsafe.
Lenome 5 Capsule can cause severe birth defects and should never be used during pregnancy. Both men and women must use effective birth control methods during treatment.

Breastfeeding:
⚠️ Consult your doctor.
Lenome 5 Capsule may pass into breast milk and harm the baby. Avoid breastfeeding during treatment.

Driving:
🚫 Unsafe.
Lenome 5 Capsule may cause dizziness, tiredness, or blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.

Kidney:
⚠️ Use with caution.
Patients with kidney disease may require dose adjustment. Consult your doctor before use.

Liver:
⚠️ Use with caution.
Dose adjustment may be required in patients with liver impairment. Regular monitoring is advised.


What if You Forget to Take Lenome 5 Capsule?

If you miss a dose, take it as soon as possible. If it’s nearly time for your next scheduled dose, skip the missed one. Do not double the dose to make up for a missed dose.


Quick Tips

  • Get regular blood tests before and during treatment to monitor blood counts.

  • Avoid activities that may cause injury or bleeding.

  • Avoid contact with people having infections (cold, flu, etc.).

  • Drink plenty of fluids to stay hydrated.

  • Apply sunscreen or wear protective clothing when outdoors, as it may cause sun sensitivity.

  • It is not recommended for children below 18 years of age.

  • Use two forms of contraception (for men and women) before, during, and 4 weeks after treatment.

  • Women of childbearing age should undergo pregnancy tests before and after treatment.

  • Inform your doctor or dentist that you are on Lenome 5 Capsule before any surgery or medical procedure.

  • You may be at risk of developing serious complications such as liver problems, severe skin reactions, or heart issues — discuss risks and benefits with your doctor.


FAQs

1. Can I take Lenome 5 Capsule on an empty stomach?
Yes, Lenome 5 Capsule can be taken with or without food. Swallow the capsule whole with water at about the same time each day.

2. Can Lenome 5 Capsule be used in dialysis patients?
Yes, it can be given after dialysis sessions. The dose may need adjustment — consult your doctor.

3. What are the possible side effects of Lenome 5 Capsule?
Common side effects include fatigue, nausea, dizziness, diarrhea, constipation, rash, joint pain, and reduced blood cell counts.

4. Does Lenome 5 Capsule increase the risk of other cancers?
Patients with multiple myeloma who receive Lenome in combination with other chemotherapy drugs may have a slightly increased risk of developing other cancers like acute myeloid leukemia (AML). Regular monitoring helps detect any issues early.

5. Do I need regular blood tests during treatment?
Yes. Blood tests are required before and during therapy to monitor white blood cells, platelets, and hemoglobin levels.

6. Do I need to use contraception while taking Lenome 5 Capsule?
Absolutely. Both men and women must use effective contraception during treatment and for 4 weeks after the final dose to prevent pregnancy-related complications.


References

Brand Name

Lenalid 5 Capsule

Generic Name

Lenalidomide

Strength

5 mg

Drug Class

Immunomodulatory Agent (IMiD) / Anti-neoplastic

Therapeutic Class

Anti-cancer / Treatment for Hematologic Malignancies

Mechanism of Action

Lenalid (Lenalidomide) is an immunomodulator that works by: 1) Enhancing the immune system's attack on cancer cells (T-cell and NK-cell activation). 2) Inhibiting angiogenesis (new blood vessel growth to tumors). 3) Directly suppressing the growth and promoting the programmed cell death (apoptosis) of malignant blood cells.

Indications (Uses)

Used in adults for the treatment of: Multiple Myeloma (MM) (in combination with Dexamethasone or as maintenance therapy), Myelodysplastic Syndromes (MDS) (specifically for transfusion-dependent anemia due to a specific chromosome deletion, $\text{del}(5\text{q})$), Mantle Cell Lymphoma (MCL), and Follicular Lymphoma (FL).

Dosage & Administration

Recommended Dose: The dose is highly variable, prescribed based on disease and renal function ($\text{CrCl}$). Typical starting doses are 10 mg once daily (for MDS or post-transplant MM maintenance) or 25 mg once daily (for MM/MCL combination therapy). Dosing is usually cyclical (e.g., daily for 21 days of a 28-day cycle). How to Take: Swallow capsule whole. Do not open, crush, or chew. Can be taken with or without food, but at the same time each day.

Common Side Effects

Hematologic Toxicity (Neutropenia, Thrombocytopenia, Anemia), Fatigue/Weakness, Diarrhea or Constipation, Nausea, Rash, Fever, Muscle/Joint pain, Dizziness.

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Lenome 5mg Lenalidomide Capsules for blood cancer and myelodysplastic syndromes. Lenome Lenalidomide 5 MG (Revl...

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