Enzalutamide 80mg: Trusted Global Cancer Care- unnatipharmax

Product introduction

Glenza 80mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Glenza 80mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Glenza Capsule

Polycystic ovarian syndrome (PCOS)
Prostate cancer
Excessive hair growth

Benefits of Glenza Capsule

In Polycystic ovarian syndrome (PCOS)

PCOS is a hormonal disorder that can cause irregular periods, ovarian cysts, and symptoms like acne or excessive hair growth. Glenza 80mg Capsule helps block the effects of certain hormones that contribute to these symptoms, supporting hormonal balance and improving menstrual regularity and skin health.

Side effects of Glenza Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glenza

Headache
Hot flashes
Weakness
High blood pressure
Fatigue
Decreased appetite
Constipation
Dry skin
Itching
Fall
Fracture

How to use Glenza Capsule

Take this medicine in the dose and duration as advised by your doctor. Glenza 80mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Glenza Capsule works

Glenza 80mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glenza 80mg Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Glenza 80mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Glenza 80mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Glenza 80mg Capsule may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Glenza 80mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Glenza 80mg Capsule may be needed. Please consult your doctor.

Liver

CAUTION

Glenza 80mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Glenza 80mg Capsule may be needed. Please consult your doctor.

What if you forget to take Glenza Capsule?

If you miss a dose of Glenza 80mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

You have been prescribed Glenza 80mg Capsule for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Glenza 80mg Capsule affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Glenza 80mg Capsule.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

FAQs

What is Glenza 80mg Capsule used for?

Glenza 80mg Capsule is used to treat prostate cancer that has spread, or is resistant to hormone therapy. It works by blocking the effect of male hormones (androgens) that help cancer cells grow.

Who should not take Glenza 80mg Capsule?

People should not take Glenza 80mg Capsule if they are allergic to it or any of its ingredients. It is also not recommended for women, especially during pregnancy, due to the risk of harm to an unborn baby.

Can Glenza 80mg Capsule cause seizures?

Yes, Glenza 80mg Capsule can increase the risk of seizures. Patients with a history of seizures, brain injury, stroke, or those taking medicines that lower the seizure threshold need extra caution.

What are the serious side effects of Glenza 80mg Capsule?

Serious side effects of Glenza 80mg Capsule may include seizures, severe allergic reactions, sudden chest pain, shortness of breath, swelling in legs, falls, memory problems, or unusual bleeding. Seek medical attention right away if these occur.

Can Glenza 80mg Capsule affect memory or thinking?

Yes, Glenza 80mg Capsule may cause problems such as memory loss, confusion, trouble concentrating, or a higher risk of falls. These side effects may impact daily activities.

Does Glenza 80mg Capsule affect blood pressure or heart health?

Yes, Glenza 80mg Capsule can cause high blood pressure, and may increase the risk of heart problems such as heart attack, or heart failure. Regular monitoring is important, especially if you already have heart disease.

Does Glenza 80mg Capsule affect fertility in men?

Yes, Glenza 80mg Capsule may reduce fertility in men, and can harm an unborn child if the father is taking it during conception. Effective contraception is recommended during treatment, and for at least 3 months after stopping.

References:-

U.S. National Library of Medicine (NIH – MedlinePlus):
- https://medlineplus.gov/druginfo/meds/a612033.html
- (General Drug Information on Enzalutamide)
U.S. Food and Drug Administration (FDA) – Drug Label (Full Prescribing Info):
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/213674s002lbl.pdf
- (Full Prescribing Information for Xtandi, confirming the 160mg standard dose which is two 80mg capsules)
NIH – PubMed Central (PMC) – Review on Efficacy and Safety:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4407758/
- (Enzalutamide for patients with metastatic castration-resistant prostate cancer)
NIH – PubMed Central (PMC) – Review on Reduced Dosing:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4106964/
- (Case study and review discussing low-dose Enzalutamide, including the 80mg dose)
Prostate Cancer UK (Patient Information Source):
- https://prostatecanceruk.org/prostate-information-and-support/treatments/enzalutamide
- (Detailed overview of Enzalutamide use for advanced prostate cancer)

Brand Name	Glenza 80mg Capsule
Generic Name	Enzalutamide
Strength	80 mg (Capsule)
Drug Class	Androgen Receptor (AR) Inhibitor / Anti-androgen
Therapeutic Class	Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)
Mechanism of Action	Glenza is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It works by blocking male hormones (androgens/testosterone) from binding to the AR, preventing AR nuclear translocation, and impairing AR interaction with DNA, thereby stopping prostate cancer cell growth.
Indications (Uses)	Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).
Dosage & Administration	Recommended Dose: The standard dose is 160 mg once daily (two 80 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.
Warnings & Precautions	Seizure Risk: Enzalutamide increases the risk of seizure (permanently discontinue if a seizure occurs). Cardiovascular Risk: Increased risk of Ischemic Heart Disease (e.g., heart attack, stroke). CNS Effects: Can cause cognitive impairment and Posterior Reversible Encephalopathy Syndrome (PRES). Drug Interactions: Enzalutamide is a strong CYP3A4 inducer and moderate CYP2C9/CYP2C19 inducer, which can decrease the concentration and effectiveness of many co-administered drugs. Contraception: Male patients must use effective contraception during treatment and for 3 months after the last dose.

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Product introduction

Uses of Glenza Capsule