Enzalutamide 160mg: Trusted Global Prostate Cancer Care

Product introduction

Enzandro 160mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Enzandro 160mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Enzandro Tablet

Polycystic ovarian syndrome (PCOS)
Prostate cancer
Excessive hair growth

Benefits of Enzandro Tablet

In Polycystic ovarian syndrome (PCOS)

PCOS is a hormonal disorder that can cause irregular periods, ovarian cysts, and symptoms like acne or excessive hair growth. Enzandro 160mg Tablet helps block the effects of certain hormones that contribute to these symptoms, supporting hormonal balance and improving menstrual regularity and skin health.

Side effects of Enzandro Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Enzandro

Headache
Hot flashes
Weakness
High blood pressure
Fatigue
Decreased appetite
Constipation
Dry skin
Itching
Fall
Fracture

How to use Enzandro Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enzandro 160mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Enzandro Tablet works

Enzandro 160mg Tablet is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Enzandro 160mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Enzandro 160mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Enzandro 160mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Enzandro 160mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Enzandro 160mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Enzandro 160mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Enzandro 160mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Enzandro 160mg Tablet may be needed. Please consult your doctor.

What if you forget to take Enzandro Tablet?

If you miss a dose of Enzandro 160mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

You have been prescribed Enzandro 160mg Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Enzandro 160mg Tablet affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Enzandro 160mg Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

FAQs

What is Enzandro 160mg Tablet used for?

Enzandro 160mg Tablet is used to treat prostate cancer that has spread, or is resistant to hormone therapy. It works by blocking the effect of male hormones (androgens) that help cancer cells grow.

Who should not take Enzandro 160mg Tablet?

People should not take Enzandro 160mg Tablet if they are allergic to it or any of its ingredients. It is also not recommended for women, especially during pregnancy, due to the risk of harm to an unborn baby.

Can Enzandro 160mg Tablet cause seizures?

Yes, Enzandro 160mg Tablet can increase the risk of seizures. Patients with a history of seizures, brain injury, stroke, or those taking medicines that lower the seizure threshold need extra caution.

What are the serious side effects of Enzandro 160mg Tablet?

Serious side effects of Enzandro 160mg Tablet may include seizures, severe allergic reactions, sudden chest pain, shortness of breath, swelling in legs, falls, memory problems, or unusual bleeding. Seek medical attention right away if these occur.

Can Enzandro 160mg Tablet affect memory or thinking?

Yes, Enzandro 160mg Tablet may cause problems such as memory loss, confusion, trouble concentrating, or a higher risk of falls. These side effects may impact daily activities.

Does Enzandro 160mg Tablet affect blood pressure or heart health?

Yes, Enzandro 160mg Tablet can cause high blood pressure, and may increase the risk of heart problems such as heart attack, or heart failure. Regular monitoring is important, especially if you already have heart disease.

Does Enzandro 160mg Tablet affect fertility in men?

Yes, Enzandro 160mg Tablet may reduce fertility in men, and can harm an unborn child if the father is taking it during conception. Effective contraception is recommended during treatment, and for at least 3 months after stopping.

References:-

Philippines Food and Drug Administration (FDA) – Drug Registration (Example):
- https://verification.fda.gov.ph/drug_productsview.php?showdetail=&registration_number=DRP-11417
- (Registration entry for ENZASTIK 40mg Softgel Capsule (Enzalutamide) in the Philippines FDA portal, confirming local approval and generic name.)
U.S. Food and Drug Administration (FDA) – Drug Label (Full Prescribing Info):
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/213674s002lbl.pdf
- (Full Prescribing Information for Xtandi, confirming the 160mg daily dosage)
NIH – PubMed Central (PMC) – Survival Study (ARCHES Trial):
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9113211/
- (Improved Survival With Enzalutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer)
NIH – PubMed Central (PMC) – Efficacy and Safety Review:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4407758/
- (Enzalutamide for patients with metastatic castration-resistant prostate cancer)
NIH – ClinicalTrials.gov – Safety/Efficacy Study:
- https://clinicaltrials.gov/study/NCT02003924?tab=results
- (Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer, using the 160mg dose)

Brand Name	Enzandro 160mg Capsule
Generic Name	Enzalutamide
Strength	160 mg
Drug Class	Androgen Receptor (AR) Inhibitor / Anti-androgen
Therapeutic Class	Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)
Mechanism of Action	Enzandro is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It blocks the effects of male hormones (androgens/testosterone) by inhibiting AR binding, preventing AR nuclear translocation, and impairing AR interaction with DNA, thus stopping prostate cancer cell growth.
Indications (Uses)	Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).
Dosage & Administration	Recommended Dose: The standard dose is 160 mg once daily (four 40 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.

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Product introduction

Uses of Enzandro Tablet