Enzalutamide 40mg / 80mg / 160mg
Enzalutamide is an oral anti-cancer medicine used in the treatment of prostate cancer. It is a next-generation androgen receptor inhibitor that blocks the action of testosterone (male hormones), thereby slowing or stopping the growth of prostate cancer cells.
Description
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Generic Name: Enzalutamide
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Available Strengths:
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40 mg capsule / tablet
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80 mg tablet
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160 mg (standard daily dose, usually taken as 4 × 40mg or 2 × 80mg tablets)
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Therapeutic Class: Androgen Receptor Inhibitor (Anti-androgen therapy)
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Route of Administration: Oral
Indications
Enzalutamide is prescribed for:
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Metastatic Castration-Resistant Prostate Cancer (mCRPC)
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Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC)
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Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
It is used in men whose disease has progressed despite androgen deprivation therapy (ADT).
Mechanism of Action
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Prostate cancer cells depend on androgens (male hormones like testosterone) to grow.
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Enzalutamide works by:
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Blocking androgen receptors.
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Preventing testosterone from binding to cancer cells.
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Inhibiting the growth and survival of prostate cancer cells.
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Dosage & Administration
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Typical adult dose: 160 mg once daily (4 × 40mg capsules OR 2 × 80mg tablets OR 1 × 160mg tablet).
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Can be taken with or without food.
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Tablets/capsules should be swallowed whole with water.
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Continue treatment until disease progression or unacceptable toxicity.
Side Effects
Common:
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Fatigue, weakness
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Hot flashes
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Hypertension
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Joint or muscle pain
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Headache
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Weight loss or decreased appetite
Serious (rare):
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Seizures
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Falls and fractures
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Heart problems (ischemic heart disease, arrhythmias)
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Posterior reversible encephalopathy syndrome (PRES – very rare)
Precautions
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Not for use in women or children (especially harmful during pregnancy).
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Can cause seizures → avoid driving or operating heavy machinery if at risk.
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Monitor blood pressure, liver function, and heart health regularly.
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Many drug interactions (especially seizure medicines, anticoagulants, CYP3A4 inducers/inhibitors).
Storage
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Store at 20°C – 25°C (room temperature).
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Keep away from direct sunlight, heat, and moisture.
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Keep out of reach of children.
FAQs
Q1. What is Enzalutamide used for?
A: It is used to treat advanced forms of prostate cancer in men, including metastatic and castration-resistant prostate cancer.
Q2. How should I take Enzalutamide 40mg / 80mg / 160mg?
A: The standard dose is 160mg once daily. Depending on strength, your doctor may prescribe multiple 40mg capsules, 80mg tablets, or a single 160mg tablet.
Q3. Can Enzalutamide cure prostate cancer?
A: No, it does not cure prostate cancer but helps control the disease, slow progression, and improve survival.
Q4. What happens if I miss a dose?
A: Take the missed dose as soon as possible on the same day. If it’s almost time for the next dose, skip the missed dose. Do not double dose.
Q5. Is Enzalutamide chemotherapy?
A: No, it is not chemotherapy. It is a targeted hormone therapy (androgen receptor inhibitor).
TRUSTED Anti Cancer MEDICINE PROVIDER – UNNATI PHARMAX
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