Bdenza Enzalutamide 160 MG (Xtandi)

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Brand Name

Bdenza 40mg Capsule

Generic Name

Enzalutamide

Strength

160mg

Drug Class

Androgen Receptor (AR) Inhibitor / Anti-androgen

Therapeutic Class

Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)

Mechanism of Action

Bdenza is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It blocks the action of male hormones (androgens/testosterone) by inhibiting AR binding, preventing AR nuclear translocation, and impairing AR interaction with DNA, thus stopping prostate cancer cell growth.

Indications (Uses)

Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).

Dosage & Administration

Recommended Dose: The standard dose is 160 mg once daily (four 40 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.

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Product introduction

Bdenza 160 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Bdenza 160 Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.


Uses of Bdenza Tablet

  • Polycystic ovarian syndrome (PCOS)
  • Prostate cancer
  • Excessive hair growth

Benefits of Bdenza Tablet

In Polycystic ovarian syndrome (PCOS)

PCOS is a hormonal disorder that can cause irregular periods, ovarian cysts, and symptoms like acne or excessive hair growth. Bdenza 160 Tablet helps block the effects of certain hormones that contribute to these symptoms, supporting hormonal balance and improving menstrual regularity and skin health.

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Side effects of Bdenza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bdenza

  • Headache
  • Hot flashes
  • Weakness
  • High blood pressure
  • Fatigue
  • Decreased appetite
  • Constipation
  • Dry skin
  • Itching
  • Fall
  • Fracture

How to use Bdenza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdenza 160 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bdenza Tablet works

Bdenza 160 Tablet is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Safety advice

warnings

Alcohol

UNSAFE
It is unsafe to consume alcohol with Bdenza 160 Tablet.
warnings

Pregnancy

CONSULT YOUR DOCTOR
Bdenza 160 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
warnings

Breast feeding

UNSAFE
Bdenza 160 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
warnings

Driving

UNSAFE
Bdenza 160 Tablet may cause side effects which could affect your ability to drive.
warnings

Kidney

CAUTION
Bdenza 160 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Bdenza 160 Tablet may be needed. Please consult your doctor.
warnings

Liver

CAUTION
Bdenza 160 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Bdenza 160 Tablet may be needed. Please consult your doctor.

What if you forget to take Bdenza Tablet?

If you miss a dose of Bdenza 160 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

FAQs

What is Bdenza 160 Tablet used for?

Bdenza 160 Tablet is used to treat prostate cancer that has spread, or is resistant to hormone therapy. It works by blocking the effect of male hormones (androgens) that help cancer cells grow.

Who should not take Bdenza 160 Tablet?

People should not take Bdenza 160 Tablet if they are allergic to it or any of its ingredients. It is also not recommended for women, especially during pregnancy, due to the risk of harm to an unborn baby.

Can Bdenza 160 Tablet cause seizures?

Yes, Bdenza 160 Tablet can increase the risk of seizures. Patients with a history of seizures, brain injury, stroke, or those taking medicines that lower the seizure threshold need extra caution.

What are the serious side effects of Bdenza 160 Tablet?

Serious side effects of Bdenza 160 Tablet may include seizures, severe allergic reactions, sudden chest pain, shortness of breath, swelling in legs, falls, memory problems, or unusual bleeding. Seek medical attention right away if these occur.

Can Bdenza 160 Tablet affect memory or thinking?

Yes, Bdenza 160 Tablet may cause problems such as memory loss, confusion, trouble concentrating, or a higher risk of falls. These side effects may impact daily activities.

Does Bdenza 160 Tablet affect blood pressure or heart health?

Yes, Bdenza 160 Tablet can cause high blood pressure, and may increase the risk of heart problems such as heart attack, or heart failure. Regular monitoring is important, especially if you already have heart disease.

Does Bdenza 160 Tablet affect fertility in men?

Yes, Bdenza 160 Tablet may reduce fertility in men, and can harm an unborn child if the father is taking it during conception. Effective contraception is recommended during treatment, and for at least 3 months after stopping.

References:-

Brand Name

Bdenza 40mg Capsule

Generic Name

Enzalutamide

Strength

160mg

Drug Class

Androgen Receptor (AR) Inhibitor / Anti-androgen

Therapeutic Class

Anti-neoplastic / Anti-cancer agents (Novel Hormone Therapy)

Mechanism of Action

Bdenza is a potent inhibitor of the Androgen Receptor (AR) signaling pathway. It blocks the action of male hormones (androgens/testosterone) by inhibiting AR binding, preventing AR nuclear translocation, and impairing AR interaction with DNA, thus stopping prostate cancer cell growth.

Indications (Uses)

Used in adult men to treat various stages of prostate cancer, including: Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-metastatic Castration-Resistant Prostate Cancer (nmCRPC) (at high risk of metastasis), and Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (often combined with ADT).

Dosage & Administration

Recommended Dose: The standard dose is 160 mg once daily (four 40 mg capsules). How to Take: Swallow capsules whole. Do not chew, dissolve, or open the capsules. Can be taken with or without food, but at the same time each day. Concurrent ADT (LHRH analog or orchiectomy) is typically required.

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Bdenza 160mg Enzalutamide Tablets for prostate cancer treatment. Bdenza Enzalutamide 160 MG (Xt...

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