Information about Axitinib
Axitinib Uses
How Axitinib works
Common side effects of Axitinib
Expert advice for Axitinib
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
- Axitinib is used for the treatment of thyroid cancer.
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
How to Use
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Axitinib should be taken exactly as prescribed by your oncologist.
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It is usually taken orally twice a day (approximately 12 hours apart).
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Can be taken with or without food.
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Swallow the tablets whole with water; do not crush or chew.
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Dosage may be adjusted based on tolerance, side effects, and response to treatment.
Side Effects
Like other TKIs, Axitinib may cause side effects.
Common side effects:
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High blood pressure (hypertension)
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Fatigue, weakness
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Diarrhea, nausea, vomiting
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Decreased appetite and weight loss
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Hand-foot syndrome (redness, pain, or swelling of palms/soles)
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Hoarseness of voice
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Headache
Serious side effects (seek immediate medical help):
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Severe bleeding or blood clots
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Heart problems (chest pain, irregular heartbeat)
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Severe high blood pressure or hypertensive crisis
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Liver problems (jaundice, dark urine, upper abdominal pain)
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Gastrointestinal perforation (rare but serious)
Precautions
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Use only under oncologist’s supervision.
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Not recommended during pregnancy or breastfeeding.
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Patients with high blood pressure, heart disease, liver problems, or history of blood clots should inform their doctor.
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Avoid grapefruit or grapefruit juice, as it may increase drug levels.
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Regular monitoring of blood pressure, liver function, and kidney function is essential.
FAQs
Q1. What is Axitinib used for?
Axitinib is used to treat advanced kidney cancer (renal cell carcinoma), particularly in patients who have previously received systemic therapy.
Q2. How does Axitinib work?
It blocks VEGF receptors, preventing the growth of blood vessels that supply tumors, thereby slowing cancer growth.
Q3. Can Axitinib cure kidney cancer?
No, it does not cure kidney cancer but helps control disease progression and improve survival.
Q4. How long will I need to take Axitinib?
Treatment continues as long as it is effective and side effects are manageable, as decided by your oncologist.
Q5. What precautions should I follow while on Axitinib?
Monitor your blood pressure regularly, avoid grapefruit products, and attend all scheduled check-ups and blood tests.
Q6. Can I take Axitinib with food?
Yes, it can be taken with or without food, but should be taken consistently the same way daily.
TRUSTED Anti Cancer MEDICINE PROVIDER – UNNATI PHARMAX
Reference:-
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European Medicines Agency (EMA) – Inlyta (Axitinib) EPAR
Comprehensive public assessment report with approval details, indications, dosing guidance, and safety data.
https://www.ema.europa.eu/en/medicines/human/EPAR/inlyta European Medicines Agency (EMA) -
European Medicines Agency (EMA) – Axitinib Accord (generic of Inlyta)
EPAR providing regulatory evaluation for the generic version, including bioequivalence confirmation.
https://www.ema.europa.eu/en/medicines/human/EPAR/axitinib-accord European Medicines Agency (EMA) -
National Cancer Institute (NCI) – Axitinib Drug Information
Authoritative overview of axitinib use, approvals, and links to further FDA labeling.
https://www.cancer.gov/about-cancer/treatment/drugs/axitinib Cancer.gov -
FDA (DailyMed) – Axitinib (Inlyta) Prescribing Information
FDA-approved official drug label detailing dosage, administration, safety, and prescribing guidelines.
(Note: Accessed via DailyMed)
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b7919013-1511-44f0-a759-3fa78a9fa178 Cancer.gov -
FDA Press Release – Approval of Avelumab (Bavencio) plus Axitinib for Advanced RCC
Regulatory update on first-line combination therapy of axitinib with avelumab for advanced renal cell carcinoma.
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-avelumab-plus-axitinib-renal-cell-carcinoma
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