Aplazar Tablet | Immunosuppressant Medicine

Product introduction

Aplazar Tablet is a nutritional supplement used in the treatment of chronic kidney disease. It reduces urea levels in the blood and helps prevent the progression of kidney disease. This way it delays the risk of undergoing long-term dialysis.

Aplazar Tablet is to be taken by mouth with or without food. Take it in the exact dose and duration as advised by the doctor. Taking it along with a low-protein diet may help get the best of the medicine. Ensure that you maintain adequate calorie intake during treatment. While you are taking this medicine, your doctor may advise regular monitoring of serum calcium levels.

There is limited data on the side effects of Aplazar Tablet. Let your doctor know if you experience any symptoms while taking Aplazar Tablet. They may be able to suggest ways to treat or manage the side effects.

Before taking Aplazar Tablet, it is important to tell your doctor if you are taking any other medicines for other health conditions. Avoid taking Aplazar Tablet if you are allergic to its ingredients, or have high calcium levels (hypercalcemia). Regular monitoring of calcium levels is recommended during use.

Avoid combining Aplazar Tablet with calcium-containing supplements or certain antibiotics (e.g., tetracyclines, quinolones) without consulting a doctor, as they may interfere with absorption. Pregnant, breastfeeding women, and individuals with liver disease should seek a doctor’s advice before use. Avoid activities requiring full mental alertness, such as driving, until you know how the medication affects you.

Uses of Aplazar Tablet

Treatment of Chronic kidney disease

Benefits of Aplazar Tablet

In Treatment of Chronic kidney disease

Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long period. CKD progresses gradually over a few years but may become permanent if left untreated. Aplazar Tablet is a combination of essential amino acids, which, when combined with a low or very low protein diet, slows down the progression of CKD and improves the quality of life.

Side effects of Aplazar Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aplazar

Limited data available

How to use Aplazar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aplazar Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Aplazar Tablet works

Aplazar Tablet belongs to a class of drugs called nutritional supplements. It follows the same catabolic pathways as amino acids and works by improving the metabolism of protein in the body, thereby improving renal function.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Aplazar Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Aplazar Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Aplazar Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Aplazar Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Aplazar Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Aplazar Tablet may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Aplazar Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Aplazar Tablet?

If you miss a dose of Aplazar Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

Taking Aplazar Tablet along with a low-protein diet helps in delaying the progression of kidney diseases and dialysis initiation.
Ensure that you maintain adequate calorie intake during therapy.
Regularly monitor serum calcium levels as instructed by your doctor. Reduce your intake of vitamin D and other calcium sources if the levels are high.

FAQs

What is Aplazar Tablet, and what is it used for?

Aplazar Tablet is a form of essential amino acid. When given as a therapy, it exerts a metabolic benefit on the body. Aplazar Tablet is most commonly used as nutrition therapy or dietary supplements in patients with chronic kidney failure. This medicine helps stop urea levels in the blood from rising too much by blocking the effects of certain amino acids that the body doesn’t need, especially in people with kidney problems.

In what disease conditions can Aplazar Tablet be used?

Most commonly, Aplazar Tablet is used as a nutritional supplement in long-term kidney disease.

Is Aplazar Tablet the same as arginine alpha-ketoglutarate?

Aplazar Tablet provides essential amino acids. It is mostly used in the prevention and treatment of damage due to faulty or deficient protein metabolism in chronic kidney disease. On the other hand, arginine alpha-ketoglutarate is a combination of the essential amino acids: arginine and alpha-ketoglutaric acid. Although both Aplazar Tablet and arginine alpha-ketoglutarate are different, their uses are almost similar.

How is Aplazar Tablet given?

The usual advice for an adult is to take the Aplazar Tablet during meals, as it helps in the proper absorption or usage of the amino acids. The Aplazar Tablet must not be chewed. Aplazar Tablet should be given along with dietary protein restriction in cases of kidney failure. The duration of treatment depends on the severity of the kidney problem. Follow your doctor’s advice, and if you notice any uneasiness/discomfort or reaction, immediately contact your doctor.

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References:-

MedlinePlus – General Alpha‑ketoacid/analogue info (covers the class of drugs Aplazar belongs to):
https://medlineplus.gov/druginfo/meds/a616017.html
National Kidney Foundation – Nutritional Supplements for CKD (discusses alpha‑ketoanalogues for renal patients):
https://www.kidney.org/atoz/content/alphaketoacid
PubChem – Alpha‑ketoacid compound info (chemical and pharmacological details relevant to Aplazar):
https://pubchem.ncbi.nlm.nih.gov/compound/Alpha-Ketoacid
NIH Clinical Trials – Studies involving alpha‑ketoacid supplementation:
https://clinicaltrials.gov/ct2/results?cond=Chronic+Kidney+Disease&term=alpha+ketoacid
WHO Model List of Essential Medicines – Renal nutrition supplements (class including alpha‑ketoanalogues):
https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02

Product Name	Aplazar Tablet
Generic Name	Sorafenib
Strength	200 mg
Form	Tablet
Manufacturer	Steadfast Medishield Pvt Ltd
Packaging	Bottle/strip of 30 tablets
Composition	Sorafenib 200 mg
Indication / Use	Advanced liver cancer (Hepatocellular Carcinoma) Advanced kidney cancer (Renal Cell Carcinoma) Advanced thyroid cancer (Differentiated Thyroid Carcinoma)
Storage	Store below 30°C in a cool, dry place away from sunlight & moisture

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Product introduction

Uses of Aplazar Tablet