Description:
Abilat 250mg Tablet contains Abiraterone Acetate, a targeted hormonal therapy used in the management of advanced prostate cancer. It is mainly prescribed for:
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Metastatic castration-resistant prostate cancer (mCRPC): Cancer that grows despite low testosterone levels.
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Metastatic high-risk castration-sensitive prostate cancer (mCSPC): Cancer that has spread and requires intensive treatment.
Abiraterone works by blocking the CYP17 enzyme, which plays a key role in producing androgens (male hormones like testosterone). Since androgens stimulate prostate cancer cell growth, lowering their levels helps to control disease progression, slow tumor growth, and improve survival outcomes.
Key Benefits:
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Effective in advanced and resistant prostate cancer cases.
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Helps improve overall survival and quality of life.
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Reduces prostate cancer–related symptoms.
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Taken orally for convenience in long-term treatment.
Common Side Effects:
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High blood pressure
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Fluid retention (swelling in feet or ankles)
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Fatigue or weakness
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Hot flashes
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Muscle or joint pain
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Low potassium levels
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Abnormal liver function tests
Precautions:
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Not recommended for women or children.
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Must be taken with prednisone to reduce side effects.
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Use with caution in patients with liver impairment, heart problems, or high blood pressure.
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Regular monitoring of potassium levels, liver function, and blood pressure is required.
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Should always be taken on an empty stomach.
Dosage & Administration:
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Standard dose: 1000mg once daily (4 tablets of 250mg each).
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Take on an empty stomach (at least 1 hour before or 2 hours after meals).
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Swallow whole with water; do not crush or chew.
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Always take alongside prednisone as prescribed by your oncologist.
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Continue as long as your doctor advises based on response and tolerance.
FAQs:
Q1: What is Abilat 250mg used for?
It is used to treat advanced stages of prostate cancer, particularly when the disease has spread or is resistant to other hormone therapies.
Q2: How does Abilat (Abiraterone) help in prostate cancer?
It blocks androgen production, which prostate cancer cells need to grow, thereby slowing down cancer progression.
Q3: Is Abilat a cure for prostate cancer?
No, it does not cure prostate cancer but it controls the disease, relieves symptoms, and prolongs survival.
Q4: Why should Abilat be taken with prednisone?
Prednisone reduces the risk of side effects like fluid retention, high blood pressure, and electrolyte imbalance.
Q5: Can I take Abilat with food?
No, it should be taken on an empty stomach, as food can increase absorption and raise the risk of side effects.
Reference:-
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https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=54ae5ef9-aea5-484a-a473-863b1397e206 DailyMed
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https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202379lbl.pdf FDA Access Database
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https://www.medicines.org.uk/emc/product/14566/smpc Medicines.org.uk
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https://rwandafda.gov.rw/wp-content/uploads/2025/06//ABIRAT250-AbirateroneAcetateTabletsUSP250mg-SmPC.pdf rwandafda.gov.rw
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https://ec.europa.eu/health/documents/community-register/2021/20210426151262/anx_151262_en.pdf
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