ABHITRUST 250MG

Abhitrust 250mg Tablet (Abiraterone Acetate)

Description:
Abhitrust 250mg Tablet contains Abiraterone Acetate, a hormonal therapy used for the treatment of advanced prostate cancer. It is mainly prescribed for patients with:

• Metastatic castration-resistant prostate cancer (mCRPC) – prostate cancer that continues to grow despite low testosterone levels.

• Metastatic high-risk castration-sensitive prostate cancer (mCSPC) – prostate cancer that has spread and requires aggressive treatment.

Abiraterone works by blocking the CYP17 enzyme, which is responsible for the production of androgens (male hormones). Since androgens fuel prostate cancer cell growth, lowering their production helps to slow tumor progression, reduce symptoms, and extend survival.

Key Benefits:

• Helps control advanced and resistant prostate cancer.

• Proven to prolong survival and delay disease progression.

• Effective even when other hormonal treatments stop working.

• Oral therapy for convenient long-term use.

Common Side Effects:

• Increased blood pressure

• Swelling in feet and ankles (fluid retention)

• Low potassium levels

• Fatigue and weakness

• Hot flashes

• Joint or muscle pain

• Liver function abnormalities

Precautions:

• Not for use in women or children.

• Must always be taken with prednisone to reduce side effects.

• Use caution if you have liver disease, heart problems, hypertension, or electrolyte imbalance.

• Requires regular monitoring of liver function, potassium levels, and blood pressure.

• Should be taken on an empty stomach to avoid excessive drug absorption.

Dosage & Administration:

• Recommended dose: 1000mg once daily (4 tablets of 250mg each).

• Take on an empty stomach (at least 1 hour before or 2 hours after meals).

• Swallow tablets whole with water; do not crush or chew.

• Always take with prednisone as advised by your doctor.

• Continue treatment as long as prescribed by your oncologist.

FAQs:

Q1: What is Abhitrust 250mg Tablet used for?
It is used to treat advanced prostate cancer in men, particularly when the cancer has spread or is resistant to other treatments.

Q2: How does Abhitrust (Abiraterone) work?
It blocks the production of androgens (male hormones), which fuel the growth of prostate cancer cells, thereby slowing disease progression.

Q3: Does Abhitrust cure prostate cancer?
No, it cannot cure prostate cancer but it can control the disease, reduce symptoms, and extend survival.

Q4: Why should Abhitrust be taken with prednisone?
Prednisone helps minimize side effects such as fluid retention, high blood pressure, and low potassium caused by Abiraterone.

Q5: How long can I take Abhitrust 250mg Tablet?
The duration depends on your treatment response and tolerance. Your doctor will guide how long you should continue therapy.

Reference:-

• https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadCommitteeFiles/Recommendations%20Oncology%2009.07.2024.pdf CDSCO

• https://clinicaltrials.gov/study/NCT02608359 ClinicalTrials

• https://pmc.ncbi.nlm.nih.gov/articles/PMC7113122/